Cytogenetics: Karyotyping / FISH; Molecular genetics: Restriction fragment length polymorphism analysis / Real time polymerase chain reaction / Multiplex polymerase chain reaction and fragment lenght analysis by capilar electrophoresis / Quantitive florescence polymerase chain reaction / Repetitive sequence based polymerase chain reaction and fragment lenght analysis by / Capilary electrophoresisamplification resistant mutation analysis technology / Long range chain polymerase reaction / Multiplex ligation-dependent probe amplification / Sanger sequencing / New generation sequencing (Ion Torrent and Illumina technologies) / Pyrosequencing / Genotype identification by polymerase chain reaction and micrarray method with / Autogenomics InfinityPlus authomatic analyser; Biochemical genetics: Liquid chromatography / Mass spectrometry